产品货号：
Z20258
中文名称：
MBD2抗体
英文名称：
Anti-MBD2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MBD2 Antibody |
| 指标别名 | Demethylase;DMTase;MBD2;NY CO 41 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | MBD2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MBD2 recombinant protein (Position:W159-A411).Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2. |
| 实际分子量 | 43KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene.It is mapped to 18q21.2.Human proteins MECP2,MBD1,MBD2,MBD3,and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD).Each of these proteins,with the exception of MBD3,is capable of binding specifically to methylated DNA.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development.The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal.It is also reported that this protein functions as a demethylase to activate transcription,as DNA methylation causes gene silencing. |
| Uniprot ID | Q9UBB5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | methyl-CpG binding domain protein 2 |
| 蛋白名全称 | Methyl-CpG-binding domain protein 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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